Beilstein J. Org. Chem.2020,16, 39–49, doi:10.3762/bjoc.16.6
; membrane-active peptides; photopharmacology; zebrafishembryotoxicitymodel; Introduction
Biologically-active peptides as a class of chemotherapeutic compounds are uniquely positioned between traditional small organic molecule drugs and high-molecular weight biologics [1][2]. Since recent breakthroughs in
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Graphical Abstract
Figure 1:
DAE photoswitch and photoswitchable peptides explored in this study. (A) The reversible photoisomer...